Hip Antibody AF1568 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHip Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF1568
NCBI Gene AliasesHhip1
ApplicationsWestern Blot
IsotypeIgG
Quantity100 ug (also 25 ug)
TargetHip
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityMouse
HostGoat
NCBI Full Gene NameHedgehog-interacting protein
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse Hip, Lys24-Arg678 (Asn29Ser), Accession # Q7TN16
ConcentrationLYOPH
PurityImmunogen affinity purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse Hip in direct ELISAs and Western blots

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Unique lingual expression of the Hedgehog pathway antagonist Hedgehog-interacting protein in filiform papillae during homeostasis and ectopic expression in fungiform papillae during Hedgehog signaling inhibitionDevelopmental dynamics : an official publication of the American Association of AnatomistsJuly 1, 2022Kumari A, Li L, Ermilov AN, Franks NE, Dlugosz AA, Allen BL, Mistretta CM.Primary antibodies were used to identify HH-antagonist HHIP (1:5000, developed in Allen lab14; 1:500, AF1568, R&D Systems), TB cells (K8, 1:1000 TROMA1, DSHB), HH ligand (SHH, 0.1 μg/ml, AF464, R&D Systems), and

(2) Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartmentsCancer researchApril 1, 2013Ehnman M, Missiaglia E, Folestad E, Selfe J, Strell C, Thway K, Brodin B, Pietras K, Shipley J, Östman A, et al.

(3) Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinomaClinical cancer research : an official journal of the American Association for Cancer ResearchJune 15, 2008Tada M, Kanai F, Tanaka Y, Tateishi K, Ohta M, Asaoka Y, Seto M, Muroyama R, Fukai K, Imazeki F, et al.

(4) Phorbol esters inhibit the Hedgehog signalling pathway downstream of Suppressor of Fused, but upstream of GliOncogeneAugust 2, 2007Lauth M, Bergström A, Toftgård R.depicted in (d), could be conﬁrmed on the protein level. a-Hip1 (R&D Systems, Minneapolis, MN, USA AF1568), a-b-Actin (Sigma-Aldrich, St Louis, MO, USA A5441). Oncogene Protein kinase Cd in Hedgehog signal

(5) Activation of the hedgehog pathway in a subset of lung cancersCancer lettersNovember 28, 2006Chi S, Huang S, Li C, Zhang X, He N, Bhutani MS, Jones D, Castro CY, Logrono R, Haque A, et al.

(6) Activation of the hedgehog pathway in advanced prostate cancerMolecular CancerOctober 13, 2004Tao Sheng, Chengxin Li, Xiaoli Zhang, Sumin Chi, Nonggao He, Kai Chen, Frank McCormick, Zoran Gatalica, Jingwu XieDetection of HIP in human cancer specimens. By Western blotting, HIP antibodies (R&D systems Cat# AF1568) recognized one band between 75 and100 KD (A). Expression of endogenous HIP was detected in two GI cancer

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Hip Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Hip Antibody from R&D Systems, a Bio-Techne Brand

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